Anguish neurosis today

The anguish of India.

Background: Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte homeostasis and immunological tolerance due primarily to genetic defects in Fas (CD95/APO-1; TNFRSF6), a cell surface receptor that regulates apoptosis and its signaling apparatus. Methods: Fas ligand gene mutations from ALPS patients were identified through cDNA and genomic DNA sequencing. Molecular and bioc...

Institutional Neurosis

Compensation neurosis.

The concept of compensation neurosis developed in the wake of the nineteenth century Industrial Revolution and subsequent enactment of workmen's compensation laws. The nosologic designation of traumatic neurosis was not consensually accepted until after World War II; the compensation label was epithetically applied as a simplistic explanation of puzzling postaccident disability. In diagnostic e...

Anguish of the abandoned child.

Communist dictator Nicolae Ceausescu banned birth control and abortion in 1966 to increase Romania’s population. Overwhelmed, parents left children by the thousands in state institutions. Romanian officials, in trying later to make up for these abuses, agreed to a study by U.S. investigators to determine the inimical effects of early life in an orphanage on the still large numbers of instituti...

Viruses, neurosis and fatigue.

The evidence for viral infections as a cause of anxiety, depression and fatigue is reviewed. It is argued that in order to fully understand any proposed relationship the effects of psychosocial factors on immunity, convalescence and illness behaviour must be acknowledged.